Dr. Jennifer Weiser
Professor of Chemical Engineering
Distinguished Professor of Bioengineering

Faculty Bio


Transdermal Patches for The Controlled-Release of Vitamin C Targeting Acne Vulgaris and Post-Inflammatory Hyperpigmentation


This project looked to address the challenge of treating acne vulgaris (AV) and its aftereffect, post-inflammatory hyperpigmentation (PIH). Acne vulgaris (AV) and post-inflammatory hyperpigmentation (PIH) are common conditions, but current treatments can be costly, inaccessible, or cause side effects. Vitamin C (L-ascorbic acid, LAA) can help both AV and PIH, but it degrades quickly when exposed to air and UV light. This study developed zinc oxide (ZnO)-infused thermoplastic polyurethane (TPU) transdermal patches with β-cyclodextrin (β-CyD) encapsulation to protect LAA and enable controlled release with zero order release kinetics over a period of 10 hours.

Theses
  • Olivia Kim – “Development of Photoprotective Transdermal Patches for The Controlled-Release of Vitamin C Targeting Acne Vulgaris and Post-Inflammatory Hyperpigmentation”
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